Biochemistry I

YOU Young-Jai Professor

Department: G30

Class Time: 2018 Fall Monday
Recommended for: G30

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Course Overview

Biochemistry is the study of the chemistry of life processes. It is the unifying principle underlying biological diversity.

Through biochemistry, we learn microscopic processes such as protein phosphorylation that regulates many signaling cascades in the cells. We also learn macroscopic processes such as evolutionarily conservation of a protein family which works similarly from bacteria to humans.

This course covers thermodynamics of a system, building blocks of principle biomolecules such as DNA and proteins, and the relationship between their structures and functions. Together, we aim to understand the mechanisms of action of the biomolecules, which allows an organism to live.

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Textbooks:

Lehninger Principles of Biochemistry, the 7th edition Principles of Biochemistry Voet & Voet, the 4th edition Biochemistry Stryer, the 8th edition

Evaluation

Midterm and final exam each  40 x 2 = 80%
Quizzes  10%
Activities + Participation  10%

Class schedule

Month Day Topic
10 15 Introduction: chemical and cellular foundations of life
22 Thermodynamics: physical foundation of life
29 Water: Physical & chemical properties of water
11   5 Amino Acids
12 Proteins: 2D structures
19 Proteins: 3D structures
26 Review session
29 EXAM
12   3 Proteins in action: Hemoglobin
10 Tools to study protein functions
17 Protein function: enzyme I
26 Protein function: enzyme II
  1   8 Nucleic acids
21 Nucleic acids: tools to understand
28 Review session
  2   4 EXAM

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Lecture Notes

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Page last updated February 12, 2020

The class contents were most recently updated on the date indicated. Please be aware that there may be some changes between the most recent year and the current page.

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